Friday, October 22, 2021

English Premier League odds, lines, plus and minus – up-to-date betting information and selections

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The English Premier League season continues with a full line-up of matchday five action between Friday and Sunday. For the first time this season, the impact of European play on weekdays will be felt in the line-up selections in matches.

The money line, over / under, margins and odds for both teams to score are outlined below for each game. Here is a list of the best recommended options, including this list of favorites:

  • Chelsea’s clean sheet: +115
  • Watford Asian Handicap Selection: +150
  • Wolves -1.5 shots on target: -120
  • Leeds Win / Draw + Over 2.5 Goals: +100

MORE: How to Watch English Premier League Matches

Odds courtesy of DraftKings and updated as of September 17.


match Victory at home Draw Visitor wins
Newcastle vs. Leeds +205 +265 +130
Wolverhampton vs. Brentford -115 +230 +390
Burnley vs. Arsenal +290 +245 +100
Man City vs. Southampton -650 +800 +1500
Liverpool vs. Crystal Palace -475 +600 +1200
Norwich City vs. Watford +120 +240 +240
Aston Villa vs. Everton +140 +240 +200
West Ham vs. Man United +350 +300 -130
Brighton vs Leicester +170 +220 +180
Tottenham vs. Chelsea +400 +280 -140


match Over 2.5 Less than 2.5
Newcastle vs. Leeds -160 +125
Wolverhampton vs. Brentford +140 -175
Burnley vs. Arsenal +105 -130
Man City vs. Southampton -245 +190
Liverpool vs. Crystal Palace -200 +160
Norwich City vs. Watford +110 -135
Aston Villa vs. Everton -105 -120
West Ham vs. Man United -150 +120
Brighton vs Leicester +110 -135
Tottenham vs. Chelsea +105 -130


Local team Away team
Newcastle +0.5 (-145) Leeds -0.5 (+130)
Wolves -0.5 (-115) Brentford +0.5 (+100)
Burnley +0.5 (-115) Arsenal -0.5 (+100)
City of Man -1.5 (-210) Southampton +1.5 (+185)
Liverpool -1.5 (-150) Crystal Palace +1.5 (+130)
Norwich -0.5 (+120) Watford +0.5 (-135)
Aston Villa -0.5 (+145) Everton +0.5 (-160)
West Ham +0.5 (+115) Man United -0.5 (-130)
Brighton -0.5 (+170) Leicester +0.5 (-195)
Tottenham +0.5 (+120) Chelsea -0.5 (-140)

Both teams will score

match BTTS – Yes Both Teams To Score – No.
Newcastle vs. Leeds -180 +140
Wolverhampton vs. Brentford +120 -155
Burnley vs. Arsenal -115 -115
Man City vs. Southampton +125 -165
Liverpool vs. Crystal Palace +110 -145
Norwich City vs. Watford -110 -115
Aston Villa vs. Everton -130 +100
West Ham vs. Man United -145 +115
Brighton vs Leicester -120 -110
Tottenham vs. Chelsea +100 -130

MORE: Champions League betting odds, futures and favorites

The best bets in the Premier League

Newcastle United vs. Leeds United

  • Date: Friday September 17
  • Weather: 3 p.m. ET
  • TV: NBCSN, Universe
  • Transmission: fuboTV

Leeds Win or Draw + Over 2.5 Goals: +100

These are the two teams with the most expected goals against in the entire league and now Leeds will also be without their suspended central defender Pascal Struijk. Goals are clearly expected (both teams to score are priced at -180), but it is Marcelo Bielsa’s sophisticated patterns and attack combinations that should triumph against an inferior Newcastle team.

Wolverhampton vs. Brentford

  • Date: Saturday September 18
  • Weather: 7:30 am ET
  • TV: NBCSN, Universe
  • Transmission: fuboTV

Wolves -1.5 shots on target: -120

The Wolves have compiled an average of 4.75 shots on goal per game, compared to Brentford’s 2.25 figure. The Wolves clearly have the best team and the most talented attackers, and their game so far should have yielded more than three points – their expected goal difference of +3.2 after four matches is the third best in the Premier League after Liverpool and Manchester City. After last week’s great victory, the Wolves will not let a home game slip away against a defensive team from Brentford.

Burnley vs. Arsenal

  • Date: Saturday September 18
  • Weather: 10 am ET
  • Transmission: fuboTV

Burnley’s Double Chance (Win or Draw): -120

Despite all the positivity from Mikel Arteta, it is too early to say that Arsenal have turned a corner despite taking the win against a defensive Norwich City last time out. There’s nothing like a trip to Turf Moor to knock you down. Sean Dyche’s team is fiercely competitive at home and while they failed to win their previous two home games, the margins have been tight and the combined expected goal difference (-0.2) tells the story. Burnley will enter this game feeling he can out-muscle and physically intimidate a young Arsenal team who may not yet be ready to start midfielder Thomas Partey from kickoff.

Manchester City vs Southampton

  • Date: Saturday September 18
  • Weather: 10 am ET
  • TV: USA Network, Universe
  • Transmission: fuboTV

Asian Handicap Manchester City -2: -135

Manchester City will experience a very different game compared to the 6-3 midweek victory against RB Leipzig in the Champions League. Southampton know how to frustrate teams, but Man City are a patient team in possession and especially with Kevin De Bruyne and Phil Foden recovered, the home team will find a way to create a multitude of opportunities. The -2 bet on Manchester City is a boost if Pep Guardiola’s men only win by two.

Liverpool vs. Crystal Palace

  • Date: Saturday September 18
  • Weather: 10 am ET
  • TV: none
  • Transmission: Peacock

Both Teams To Score: +110

Patrick Vieira’s teams usually need time to find their rhythm, but Crystal Palace looked like a team already comfortable in their own skin in the 3-0 win against a Tottenham team that was reduced to 10 men. Vieira’s players will not win the game against Liverpool, and there is a chance it will get ugly, but they will not be afraid to express themselves and should be good enough for a goal. Liverpool have only conceded once in the league this year, but their expected goals against in four games are 4.2.

Norwich City vs. Watford

  • Date: Saturday September 18
  • Weather: 10 am ET
  • TV: none
  • Transmission: Peacock

Watford Asian Handicap Pick: +150 (tie = push)

These teams have two of the three lowest expected goals in the Premier League, but both teams have faced superior opposition, including Norwich who had to go through teams like Liverpool, Manchester City, Arsenal and Leicester City to start the season. This will be a showdown of equals in a battle to avoid relegation. As a home team, Norwich is expected to take more chances in attack, which will expose them on defense. Watford have the weapons to capitalize and they did so last year when they visited Norwich in the Second Division. The Asian Handicap pick’em is a “no bet draw” with slightly better odds.

Aston Villa vs. Everton

  • Date: Saturday September 18
  • Weather: 12:30 pm ET
  • TV: NBC, Universe
  • Transmission: fuboTV, Peacock

Richarlison scorer at any time: +185

Without Dominic Calvert-Lewin, who is out with injury, Richarlison will lead Everton’s attack line and should have more room to operate than in the game against Burnley. His best scoring streak last season came as a center forward with four consecutive goal games (February-March 2021), and this season he has help. If wingers Demarai Gray and Andros Townsend can continue their strong start to the season, Richarlison should be at the end of a handful of Everton chances in this game, especially if the Toffees can show off their transitional play.

West Ham vs. Manchester United

  • Date: Sunday September 19
  • Weather: 9 am ET
  • TV: NBCSN, Telemundo
  • Transmission: fuboTV

West Ham Asian handicap pick in 1st half: +195 (tie = push)

West Ham have two fewer days off after their European away game on weekdays compared to Manchester United, but manager David Moyes substituted and rested other players to form a lineup strong enough to give Man trouble. United. His biggest problem will be the loss of starting center forward Michail Antonio to suspension. If anything, it could make West Ham a bit more unpredictable in their first test of the season against a superior team.

MORE: Manchester United 2021-22 Season Match Schedule

Manchester United are the best team on paper, but one wonders if any doubts will start to arise after their loss to Young Boys and the questions surrounding manager Ole Gunnar Solskjaer. The Red Devils could need the entire first half on the road to orient themselves against a tough Moyes team.

Brighton vs Leicester City

  • Date: Sunday September 19
  • Weather: 9 am ET
  • TV: none
  • Transmission: Peacock

Both Teams To Score – NO: -110

Brighton and Leicester are in the lower half of expected goals and shot creation so far this Premier League season, in part due to talent constraints (Brighton) and tactical approach (Leicester). The Foxes are usually a fast-break team on the road and can defend an advantage (22 wins the last 25 times they took the lead in the EPL). Brighton also posted the fifth most clean sheets last season with their current manager (12) with Leicester just behind with 11. Finally, since last season, half of Brighton’s home games in all competitions have seen one team did not score, including two out of two this year.

Tottenham vs. Chelsea

  • Date: Sunday September 19
  • Weather: 11:30 am ET
  • TV: none
  • Transmission: Peacock

Chelsea clean sheet: +115

Chelsea’s clean sheet odds are too good to pass up when talking about the best defensive team in the Premier League (they allowed one goal in four games and came from the penalty spot) with an extra two days of rest and the lap. by N’Golo Kante, which will be available. Tottenham could also have a major lineup change: Heung-min Son did not play midweek and attackers Lucas Moura and Stephen Bergwijn are possible absences depending on the status of their injuries picked up in Thursday’s Conference League game.

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